(C) 2012 Published by Elsevier Masson SAS.”
“The ultrasonication process (UE) was employed to efficiently extract relatively hard fruits of A. melanocarpa (Aronia) by comparing the results from conventional extractions: hot water (WE), 70% ethanol extractions (EE). 104.5 mg ml(-1) of the highest total polyphenol content was observed from the UE process as well as high amounts of two anthocyanins in A. melanocarpa such as cyanidin and dephinidin which should result in the best PARP inhibitor antioxidant activities as 70.93 % in DPPH free radical scavenging ability. Approximately

70% inhibition of melanin synthesis was also observed in adding the extracts from the UE which was also highest inhibition. It was also found that the whitening activities of the extract from the UE seemed to be better than those of each of components like cyanidin and dephinidin which implies

that the extract might be effective in maintaining its biological activities rather than using each of single components, possibly due to synergistic effects of the bioactive substances in the extracts. It was also first shown Apoptosis inhibitor that the whitening activities of the extract from the UE process were possibly associated with strong antioxidant activities of A. melanocarpa.”
“Objective: Prior research supports the hypothesis that cancer survivors who help others face treatment experience a range of psychosocial and health-related benefits as a result of peer helping. This study investigates an expressive helping (EH) intervention designed to harness those benefits by targeting survivorship click here problems among cancer survivors treated with hematopoietic stem cell transplant. EH includes two components: (a) emotionally

expressive writing (EW; writing one’s deepest thoughts and feelings about the transplant experience in a series of brief, structured writing sessions) followed by (b) peer helping (PH; helping other people prepare for transplant by sharing one’s own transplant experiences along with advice and encouragement through a written narrative). Method: EH was compared with neutral writing (NW), EW (without PH), and PH (without EW) in a 4-arm randomized controlled trial in which survivors completed baseline measures, 4 structured writing exercises (with instructions depending on randomization), and postintervention measures including validated measures of general psychological distress, physical symptoms, and health-related quality of life (HRQOL). Results: Among survivors with moderate-severe survivorship problems, EH reduced distress (compared with NW and PH; ps smaller than .05) and improved physical symptoms (compared with NW, PH, and EW; ps smaller than .002) and HRQOL (compared with NW; p = .02). Conclusions: Peer helping through writing benefits transplant survivors with moderate-severe survivorship problems, but only if they have first completed expressive writing.