ResultsA continuous zeolite layer
cannot be formed on the surface of the irregular AC particles, even when pretreated by air oxidation or concentrated nitric acid, but can be synthesized using the alumina intermediate layer method. A catalytic test of CoZr/AC@ZSM-5 indicates that the zeolite layer shell has a marked effect on product distributions.
ConclusionAided by the alumina intermediate layer, zeolite crystals nucleate at the support/solution interface rather than in solution. For Fischer-Tropsch synthesis over CoZr/AC@ZSM-5, the product distributions are shifted to methane and light hydrocarbon compared with that of CoZr/AC. (c) 2013 Society of Chemical Industry”
“Background: Pulmonary hypertension (PH) can lead to right-side heart failure (RHF) Selonsertib concentration and death. There are no therapeutic recommendations for patients experiencing acute RHF in the course of PH. This study aimed to examine the safety and efficacy of inhaled iloprost in patients with precapillary
PH and RHF.
Methods and Results: Between October 2007 and December 2008, 7 patients with precapillary PH and RHF were enrolled. Per protocol, iloprost was inhaled hourly for a minimum of 12 hours during a 24-hour period. The starting dose of 2.5 mu g was increased hourly by 2.5 mu g as GSK3235025 long as the increases were tolerated. Safety and efficacy were determined Selleckchem AC220 by continuous invasive monitoring of systemic and pulmonary hemodynamic parameters. Systemic pressures remained stable during inhalation (66.1 +/- 6.9 mm Hg at baseline and 69.1 +/- 6.4 mm Hg immediately after inhalation therapy, P = 0.48). Cardiac index increased from 2.4 +/- 0.7 L/min/m(2) to 2.9 +/- 0.9 L/min/m(2) (P = .008). Pulmonary vascular resistance decreased from 634.6 +/- 218.3 dyn.s.cm(-5) to 489.6 +/- 173.8 dyn.s.cm(-5) (P = .044), and N-terminal B-type natriuretic peptide levels decreased from 13,591 +/- 10,939 pg/mL to 9,944 +/- 8,569 pg/mL (P = .051).
Conclusion: Blood pressure-guided hourly inhalation of iloprost may offer
a safe and effective strategy for the treatment of PH patients with RHF. (J Cardiac Fail 2011;17:813-818)”
“Reproduction of flowering plants requires the growth of pollen tubes to deliver immotile sperm for fertilization. Pollen tube growth resembles that of polarized metazoan cells, in that some molecular mechanisms underlying cell polarization and growth are evolutionarily conserved, including the functions of Rho GTPases and the dynamics of the actin cytoskeleton. However, a role for AGC kinases, crucial signaling mediators in polarized metazoan cells, has yet to be shown in pollen tubes. Here we demonstrate that two Arabidopsis AGC kinases are critical for polarized growth of pollen tubes. AGC1.5 and AGC1.7 are pollen-specific genes expressed during late developmental stages.