Am J Crit Care 2003,12(4):367–371.PubMed 70. Brandt S, Regueira T, Bracht H, Porta F, Djafarzadeh S, Takala J, Gorrasi J, Borotto E, Krejci V, Hiltebrand LB, Bruegger LE, Beldi G, Wilkens L, Lepper PM, Kessler U, Jakob SM: Effect of fluid resuscitation on mortality and organ function in experimental sepsis models. Crit Care 2009,13(6):R186.PubMedCentralPubMed 71. Harvey S, Young D, Brampton W, Cooper AB, Doig G, Sibbald W, Rowan K: Pulmonary artery catheters for adult patients in intensive care. Cochrane Database Syst Rev 2006.,19(3): CD003408 72. Charron C, Caille V, Jardin F, Vieillard-Baron A: Echocardiographic measurement of fluid responsiveness. Tucidinostat Curr Opin Crit Care 2006,12(3):249–254.PubMed 73. Manasia

AR, Nagaraj HM, Kodali RB, Croft LB, Oropello JM, VS-4718 order Kohli-Seth

R, Leibowitz AB, DelGiudice R, Hufanda JF, Benjamin E, Goldman ME: Feasibility and potential clinical utility of goal-directed CA4P transthoracic echocardiography performed by noncardiologist intensivists using a small hand-carried device (SonoHeart) in critically ill patients. J Cardiothorac Vasc Anesth 2005,19(2):155–9.PubMed 74. Zhang Z, Xu X, Yao M, Chen H, Ni H, Fan H: Use of the PiCCO system in critically ill patients with septic shock and acute respiratory distress syndrome: a study protocol for a randomized controlled trial. Trials 2013, 14:32.PubMedCentralPubMed 75. Martin C, Papazian L, Perrin G, Saux P, Gouin F: Norepinephrine or dopamine for the treatment of hyperdynamic septic shock? Chest 1993,103(6):1826–1831.PubMed 76. de Backer D, Aldecoa C, Njimi H, Vincent JL: Dopamine versus norepinephrine in the treatment CYTH4 of septic shock: a meta-analysis*. Crit Care Med 2012,40(3):725–730.PubMed 77. Regnier B, Rapin M, Gory G, Lemaire F, Teisseire B, Harari A:

Haemodynamic effects of dopamine in septic shock. Intensive Care Med 1977, 3:47–53.PubMed 78. Seguin P, Bellissant E, Le Tulzo Y, Laviolle B, Lessard Y, Thomas R, Mallédant Y: Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clin Pharmacol Ther 2002, 71:381–388.PubMed 79. Myburgh JA, Higgins A, Jovanovska A, CAT Study investigators: A comparison of epinephrine and norepinephrine in critically ill patients. Intensive Care Med 2008, 34:2226–2234.PubMed 80. Holmes CL, Patel BM, Russell JA, Walley KR, Walley KR: Physiology of vasopressin relevant to management of septic shock. Chest 2001, 120:989–1002.PubMed 81. White LE, Hassoun HT, Bihorac A, Moore LJ, Sailors RM, McKinley BA, Valdivia A, Moore FA: Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis. J Trauma Acute Care Surg 2013,75(3):432–438.PubMed 82. Marshall JC: Principles of source control in the early management of sepsis. Curr Infect Dis Rep 2010,12(5):345–353.PubMed 83. Marshall JC, al Naqbi A: Principles of source control in the management of sepsis. Crit Care Clin 2009,25(4):753–768.PubMed 84.