This was enhanced by NHS CRD evaluation through Perifosine msds a range of studies to examine the effects of family-based intervention, which focussed on two factors; to assess the parent as the agent and behavioural modification programmes [10]. It has been found that the parent-as-agent group could help to reduce the weight of the children [27]. From a different perspective, schools influence the lives of most children and therefore act as a platform for health education and health promotion regarding diet, physical activity and other healthy behaviour [27]. They also play an active role in encouraging children to adopt and maintain healthy eating habits and increase physical activity (CDC).

Veugelers and Fitzgerald [28] examined the efficacy of school-based programs for childhood obesity and concluded that school acts as a platform for children to enhance their future health and wellbeing by eating healthily and encouraging physical activity. Since the framework of school-based intervention may improve and provide social benefits, it will improve the child��s health throughout the critical period of growth and maturation and help them to continue healthy habits throughout their lives [29]. Even though dietary habits, healthy lifestyle education, physical activity and involvement of parents have been accepted as modifiable variables, which are linked to evidence of childhood obesity, a true understanding of all causative factors is imprecise [30]. This made it evident that there is degree of variability prevailing in methodological and theoretical underpinning among school-based programs making the evaluation of the effectiveness of outcomes more complex [29].

Meta-analysis by Suarez et al. [31] found that school-based intervention is effective in decreasing and managing childhood obesity, but not in reducing BMI in intervention groups when compared to control groups. This result contrasts with that of Katz et al. [32] where nutrition and physical activity intervention showed a significant decrease in BMI in the intervention group when compared to the control group. In a review by Sharma [17], the intervention carried out in upper elementary and lower middle schools was most helpful in the treatment and prevention of childhood obesity. Furthermore, systematic reviews by Connelly et al. [33] and Ells et al.

[34] showed that the effectiveness of school-based interventions is extremely limited with insufficient quality and outcome, which was recommended through Katz et al. [32]. The reviews also showed that there is only a small number of Randomised controlled Trial��s (RCTs) and only a few on the treatment of childhood Anacetrapib obesity [35]. High-quality research evidence focuses on intervention components such as physical activity, lifestyle, drug and surgical intervention for the treatment of childhood obesity [11].